Biochem/physiol Actions

Target Sub-Family: TK

Protein Target: Met

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation D1246N

Product Source: expressed by baculovirus in Sf21 insect cells

Met D1246N is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). In vitro studies have demonstrated enhanced kinase activity from this mutant.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Packaging

Available in 250 µg --call for pricing and availability and reference catalog number 14-818M when ordering the 250 µg size.

Physical form

Ni²⁺/NTA-agarose

Storage and Stability

6 months at -70°C